CMKLR1 anticorps (AA 151-250) (Cy7)
Aperçu rapide pour CMKLR1 anticorps (AA 151-250) (Cy7) (ABIN1709007)
Antigène
Voir toutes CMKLR1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 151-250
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Fonction
- CMKLR1 Polyclonal Antibody, Cy7 Conjugated
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Réactivité croisée
- Humain, Souris
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Homologie
- Dog,Sheep
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from mouse CMKLR1
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Isotype
- IgG
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Indications d'application
- WB(1:300-5000), FCM(1:20-100), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
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Autre désignation
- CMKLR1
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Sujet
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Synonyms: DEZ, Gpcr27, ChemR23, mcmklr1, Chemokine-like receptor 1, G-protein coupled receptor DEZ, Cmklr1
Background: Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B (By similarity). Positively regulates adipogenesis and adipocyte metabolism.
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ID gène
- 14747
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UniProt
- P97468
Antigène
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