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BPY2 anticorps (AA 51-106) (FITC)

BPY2 Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal FITC
N° du produit ABIN1709078
  • Antigène Voir toutes BPY2 Anticorps
    BPY2 (Basic Charge, Y-Linked, 2 (BPY2))
    Épitope
    • 14
    • 1
    AA 51-106
    Reactivité
    Humain
    Hôte
    • 15
    Lapin
    Clonalité
    • 15
    Polyclonal
    Conjugué
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BPY2 est conjugé à/à la FITC
    Application
    • 15
    • 12
    • 12
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human BPY2
    Isotype
    IgG
    Top Product
    Discover our top product BPY2 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    BPY2 (Basic Charge, Y-Linked, 2 (BPY2))
    Autre désignation
    BPY2 (BPY2 Produits)
    Synonymes
    anticorps BPY2A, anticorps VCY2, anticorps VCY2A, anticorps basic charge, Y-linked, 2, anticorps BPY2
    Sujet

    Synonyms: Basic charge, Basic charge Y linked 2, Basic charge Y linked 2C, Basic protein on Y chromosome 2, BPY2A, BPY2B, BPY2C, Testis specic basic protein on Y 2, Testis specic basic protein Y 2, Testis-specic basic protein Y 2, Variable charge Y linked 2, Variably charged protein Y 2, VCY2, VCY2_HUMAN, VCY2A, VCY2B, VCY2C, Y-linked 2.

    Background: Mammalian spermatogenesis is a complex developmental process. Mutations at multiple loci and in structurally and functionally disparate genes in the genome affect gametogenesis. The analysis of mutations has provided insight into biochemical pathways required for completion of this process. The basic protein on Y chromosome 2 gene (BPY2, also designated VCY2) is located in a frequently deleted azoospermia factor c region. Three copies (paralogs) of the BPY2 gene (BPY2A, BPY2B, BPY2C) reside in the AZFc region. BPY2 protein expression is localized to the nuclei of spermatogonia, spermatocytes and round spermatids, but is absent from elongated spermatids. Impaired expression of BPY2 in infertile men suggests its involvement in male germ cell development. BPY2 interacts with MAP-1S, which shares homology with microtubule-associated proteins (MAPs), suggesting a role for BPY2 within the cytoskeletal network.

    ID gène
    442867
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