GADL1 anticorps (AA 51-150) (FITC)

N° du produit ABIN1709503

Cet anticorps Lapin Polyclonal détecte spécifiquement GADL1 dans IF (cc) et IF (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour GADL1 anticorps (AA 51-150) (FITC) (ABIN1709503)

Antigène: GADL1 (Glutamate Decarboxylase-Like 1 (GADL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GADL1 est conjugé à/à la FITC

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-GADL1 anticorps (FITC)

Épitope: AA 51-150

Fonction: GADL1 Polyclonal Antibody, FITC Conjugated

Réactivité croisée: Souris, Rat

Homologie: Human,Bee

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GADL1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur GADL1

Antigène: GADL1 (Glutamate Decarboxylase-Like 1 (GADL1))

Autre désignation: GADL1

Sujet:

Synonyms: GADL1, GADL1_HUMAN, Glutamate decarboxylase like 1, Glutamate decarboxylase-like protein 1, MGC138191, OTTHUMP00000161199, OTTHUMP00000222306.

Background: There are two forms of glutamic acid decarboxylases (GADs) that exist in brain: GAD-65 (also known as GAD2) and GAD-67 (also known as GAD1, GAD or SCP). GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 transiently activates to assist in GABA production. As a member of the group II decarboxylase family, GADL1 (Glutamate decarboxylase-like protein 1) is a 521 amino acid protein that utilizes pyridoxal phosphate as a cofactor for its carboxylase activity. There are two isoforms of GADL1 that exist as a result of alternative splicing events.

ID gène: 339896