CATSPER4 anticorps (AA 101-200) (HRP)
Aperçu rapide pour CATSPER4 anticorps (AA 101-200) (HRP) (ABIN1710974)
Antigène
Voir toutes CATSPER4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 101-200
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Homologie
- Human
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human CATSPER4
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- CATSPER4 (Cation Channel, Sperm Associated 4 (CATSPER4))
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Autre désignation
- CATSPER4
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Sujet
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Synonyms: CTSR4_HUMAN, Cation channel sperm-associated protein 4, CatSper4, CatSper-4, cation channel, sperm-associated 4.
Background: CatSpers (cation channel, sperm associated proteins) are ion transport proteins located on the surface of sperm cells in the principal piece of the sperm tail. CatSpers are vital to sperm motility, fertilization and cAMP-mediated calcium influx in sperm. There are four CatSper proteins in mammalian sperm, namely CatSper (or CatSper1), CatSper2, CatSper3 and CatSper4. CatSper proteins contain a single, six-transmembrane-spanning segment and exhibit the voltage-dependent Ca2+ channel four-repeat structure. CatSper proteins are believed to assemble into a heterotetrameric complex, forming an alkalinization-activated Ca2+-selective channel. Mutations in any of the genes encoding CatSper family proteins can result in male infertility. CatSper3 plays an important role in the hyperactivated motility of sperm cells, a process that is required in the preparation of sperm for fertilization.
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ID gène
- 378807
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UniProt
- Q7RTX7
Antigène
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