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HESX Homeobox 1 anticorps (AA 51-150) (HRP)

Cet anticorps anti-HESX Homeobox 1 est un anticorps Lapin Polyclonal détectant HESX Homeobox 1 dans ELISA, IHC (fro) et IHC (p). Adapté pour Rat.
N° du produit ABIN1711047

Aperçu rapide pour HESX Homeobox 1 anticorps (AA 51-150) (HRP) (ABIN1711047)

Antigène

Voir toutes HESX Homeobox 1 (HESX1) Anticorps
HESX Homeobox 1 (HESX1)

Reactivité

  • 16
  • 13
  • 4
Rat

Hôte

  • 23
  • 4
Lapin

Clonalité

  • 25
  • 2
Polyclonal

Conjugué

  • 10
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp HESX Homeobox 1 est conjugé à/à la HRP

Application

  • 13
  • 13
  • 11
  • 7
  • 2
  • 2
  • 1
  • 1
ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Épitope

    • 14
    • 7
    • 1
    • 1
    • 1
    AA 51-150

     Réactivité croisée

    Rat

    Homologie

    Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

    Purification

    Purified by Protein A.

    Immunogène

    KLH conjugated synthetic peptide derived from human HESX1

    Isotype

    IgG
  • Indications d'application

    IHC-P 1:200-400
    IHC-F 1:100-500

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Conseil sur la manipulation

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Date de péremption

    12 months
  • Antigène

    HESX Homeobox 1 (HESX1)

    Autre désignation

    HESX1

    Sujet

    Synonyms: NULL

    Background: The homeobox protein, HESX1, which is also known as Rathke?s pouch homeobox, HANF, homeodomain transcription factor, and anterior-restricted homeobox protein is a transcription factor that belongs to the homeodomain family of DNA binding proteins. HESX1 is initially expressed in embryonic stem cells and the primitive forebrain, and is essential for normal development of the eyes and other anterior CNS structures, such as the hypothalamus, the pituitary gland and the olfactory bulbs. The homeobox gene Hesx1 is expressed in the anterior visceral endoderm (AVE), anterior axial mesendoderm (AME), and anterior neural ectoderm (ANE) during early embryogenesis. Mutations in the Hesx1 gene are associated with disorders that are comparable with septo-optic dysplasia (SOD). These disorders are characterized by hypoplasia of the optic nerve, various types of forebrain defects and pituitary hormone deficiencies, including hypothyroidism. Hesx1 also acts as a transcriptional repressor of reporter gene constructs in tissue culture assays.

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