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CTBS anticorps (AA 1-100) (HRP)

CTBS Reactivité: Souris WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1711269
  • Antigène Voir toutes CTBS Anticorps
    CTBS (Chitobiase, Di-N-Acetyl (CTBS))
    Épitope
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reactivité
    • 17
    • 13
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 23
    • 3
    • 1
    Lapin
    Clonalité
    • 25
    • 2
    Polyclonal
    Conjugué
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CTBS est conjugé à/à la HRP
    Application
    • 27
    • 13
    • 13
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Souris
    Homologie
    Human,Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human CTBS
    Isotype
    IgG
    Top Product
    Discover our top product CTBS Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    CTBS (Chitobiase, Di-N-Acetyl (CTBS))
    Autre désignation
    CTBS (CTBS Produits)
    Synonymes
    anticorps CTB, anticorps 2210401K11Rik, anticorps chitobiase, anticorps chitobiase, di-N-acetyl-, anticorps CTBS, anticorps Ctbs
    Sujet

    Synonyms: Chitobiase di N acetyl, CTB, Di N acetylchitobiase, OTTHUMP00000011570, DIAC_HUMAN.

    Background: CTBS is an evolutionarily conserved member of the glycosyl hydrolase 18 family of proteins. Localizing to the lysosome, CTBS plays a role in the degradation of asparagine-linked (Asn-linked) glycoproteins. Glycoproteins are translocated to lysosomes via endocytosis or autophagy where they are broken down by proteases and glycosidases. The catabolism of glycoproteins is an important step in the regular turnover of cellular contents and in maintaining the homeostasis of glycosylation. CTBS functions as a glycosidase that cleaves the reducing end GlcNAc from the core chitobiase unit of oligosaccharides. Before this reaction can occur, AGA (the lysosomal glycosylasparaginase) must first remove the Asn from the Asn-linked glycoprotein to expose the reducing end GlcNAc, thereby allowing CTBS to access the exposed moiety.

    ID gène
    1486
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