ERMAP anticorps (AA 61-120) (HRP)

N° du produit ABIN1711294

Cet anticorps Lapin Polyclonal détecte spécifiquement ERMAP dans ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour ERMAP anticorps (AA 61-120) (HRP) (ABIN1711294)

Antigène: ERMAP (erythroblast Membrane-Associated Protein (Scianna Blood Group) (ERMAP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERMAP est conjugé à/à la HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-ERMAP anticorps (HRP)

Épitope: AA 61-120

Homologie: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ERMAP

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ERMAP

Antigène: ERMAP (erythroblast Membrane-Associated Protein (Scianna Blood Group) (ERMAP))

Autre désignation: ERMAP

Sujet:

Synonyms: ERMAP, ERMAP_HUMAN, Erythroblast membrane associated protein, Erythroid membrane associated protein, Erythroid membrane-associated protein, hERMAP, MGC118810, MGC118811, MGC118812, MGC118813, PRO2801, Radin blood group Rd, Radin blood group antigen, RD, SC, Scianna blood group Sc, Scianna blood group antigen.

Background: ERMAP is a single-pass type one membrane protein that belongs to the immunoglobulin superfamily. Expressed in cord blood, fetal liver and adult bone marrow, ERMAP is thought to function as a cell adhesion molecule in erythroid cells and is responsible for expression of the Scianna/Radin (Sc/Rd) blood group antigen system. The Sc/Rd system is comprised of seven antigens that are present on the surface of red blood cells and have a variety of functions ranging from protein transport to cell adhesion. These seven blood antigens can differ in their expression within a population and may sometimes differ between mother and child. A fetus expressing different blood antigens than its mother may cause the mother to produce against the fetal blood. This condition is known as hemolytic disease of the newborn (HDN) and is characterized by jaundice, anemia and in some cases, infant death.

ID gène: 114625