IRF6 anticorps (AA 1-100) (HRP)

N° du produit ABIN1711367

L’anticorps Lapin Polyclonal anti-IRF6 a été validé pour WB et ELISA. Il convient pour détecter IRF6 dans des échantillons de Humain et Souris.

Aperçu rapide pour IRF6 anticorps (AA 1-100) (HRP) (ABIN1711367)

Antigène: IRF6 (Interferon Regulatory Factor 6 (IRF6))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF6 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA

Détail du produit anti-IRF6 anticorps (HRP)

Épitope: AA 1-100

Réactivité croisée: Humain, Souris

Homologie: Rat,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human IRF6

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur IRF6

Antigène: IRF6 (Interferon Regulatory Factor 6 (IRF6))

Autre désignation: IRF6

Sujet:

Synonyms: Interferon regulatory factor 6, IRF 6, IRF-6, IRF6, IRF6_HUMAN, LPS, OFC 6, OFC6, OTTHUMP00000034677, OTTHUMP00000034678, PIT, PPS, PPS1, VWS, VWS1.

Background: Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-alpha and beta) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-alpha and interferon-beta genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth, overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3 gamma p48 and IFN consensus sequence-binding protein (ICSBP).