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MYCBPAP anticorps (AA 401-500) (HRP)

MYCBPAP Reactivité: Rat, Souris IHC (fro), IHC (p) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1711382
  • Antigène Voir toutes MYCBPAP Anticorps
    MYCBPAP (MYCBP Associated Protein (MYCBPAP))
    Épitope
    • 14
    • 1
    • 1
    AA 401-500
    Reactivité
    • 16
    • 15
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Rat, Souris
    Hôte
    • 18
    Lapin
    Clonalité
    • 18
    Polyclonal
    Conjugué
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MYCBPAP est conjugé à/à la HRP
    Application
    • 13
    • 13
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Human
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human MYCBPAP
    Isotype
    IgG
  • Indications d'application
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C/-80 °C
    Stockage commentaire
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Date de péremption
    12 months
  • Antigène
    MYCBPAP (MYCBP Associated Protein (MYCBPAP))
    Autre désignation
    MYCBPAP (MYCBPAP Produits)
    Synonymes
    anticorps AMAP-1, anticorps AMAP1, anticorps 4932408B01Rik, anticorps AW125474, anticorps COD106, anticorps MYCBP associated protein, anticorps Mycbp associated protein, anticorps MYCBPAP, anticorps Mycbpap
    Sujet

    AMAP-1 (AMY-1-binding protein 1), also known as AMAM-1 or MYCBPAP (MYCBP associated protein), is a 947 amino acid protein that is expressed specifically in testis and is involved in spermatogenesis and synaptic processes. AMAP-1 colocalizes with MYCBP (AMY-1) in cytoplasm and also localizes to membrane. The gene encoding AMAP-1 maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

    Subcellular location: Cytoplasm, Cell membrane

    Synonyms: AMAM-1, AMAP-1, AMAP1, AMY-1-binding protein 1, DKFZp434N1415, MYBPP_HUMAN, MYCBP-associated protein, Mycbpap.

    Pathways
    Sensory Perception of Sound
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