BTBD14A anticorps (AA 401-500) (HRP)

N° du produit ABIN1711556

L’anticorps Lapin Polyclonal anti-BTBD14A a été validé pour ELISA, IHC (p) et IHC (fro). Il convient pour détecter BTBD14A dans des échantillons de Humain.

Aperçu rapide pour BTBD14A anticorps (AA 401-500) (HRP) (ABIN1711556)

Antigène: BTBD14A (BTB (POZ) Domain Containing 14A (BTBD14A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BTBD14A est conjugé à/à la HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-BTBD14A anticorps (HRP)

Épitope: AA 401-500

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human BTBD14A

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur BTBD14A

Antigène: BTBD14A (BTB (POZ) Domain Containing 14A (BTBD14A))

Autre désignation: BTBD14A

Sujet:

Synonyms: BTB POZ domain containing 14A, BTB domain containing 14A, BTB/POZ domain containing protein 14A, BTB/POZ domain-containing protein 14A, BTBD 14A, BTBD14, NAC-2, NACC2, NACC2_HUMAN, Nucleus accumbens-associated protein 2.

Background: BTBD14A is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.

ID gène: 54813

Pathways: Positive Regulation of Response to DNA Damage Stimulus