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C1orf174 anticorps (AA 161-243) (HRP)

C1orf174 Reactivité: Humain WB, IHC (p), IHC (fro) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1712011
  • Antigène Tous les produits C1orf174
    C1orf174 (Chromosome 1 Open Reading Frame 174 (C1orf174))
    Épitope
    • 14
    • 1
    AA 161-243
    Reactivité
    Humain
    Hôte
    • 15
    Lapin
    Clonalité
    • 15
    Polyclonal
    Conjugué
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp C1orf174 est conjugé à/à la HRP
    Application
    • 13
    • 13
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human C1orf174
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C/-80 °C
    Stockage commentaire
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Date de péremption
    12 months
  • Antigène
    C1orf174 (Chromosome 1 Open Reading Frame 174 (C1orf174))
    Autre désignation
    C1orf174 (C1orf174 Produits)
    Synonymes
    anticorps C1orf174, anticorps RP13-531C17.2, anticorps chromosome 21 C1orf174 homolog, anticorps chromosome 1 open reading frame 174, anticorps chromosome 16 C1orf174 homolog, anticorps C21H1orf174, anticorps C1orf174, anticorps C16H1orf174
    Sujet

    Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf174 gene product has been provisionally designated C1orf174 pending further characterization.

    Subcellular location: Nucleus

    Synonyms: C1orf174, CA174_HUMAN, Chromosome 1 open reading frame 174, Hypothetical protein LOC339448, OTTHUMP00000003854, RP13-531C17.2, UPF0688 protein C1orf174.

    ID gène
    339448
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