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NERP-2 anticorps (AA 301-400) (HRP)

NERP-2 Reactivité: Poisson zèbre (Danio rerio) IHC (p), IHC (fro) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1712081
  • Antigène Voir toutes NERP-2 Anticorps
    NERP-2 (Neuroendocrine Regulatory Peptide 2 (NERP-2))
    Épitope
    • 14
    • 1
    AA 301-400
    Reactivité
    • 14
    • 10
    • 9
    Poisson zèbre (Danio rerio)
    Hôte
    • 33
    Lapin
    Clonalité
    • 33
    Polyclonal
    Conjugué
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NERP-2 est conjugé à/à la HRP
    Application
    • 13
    • 13
    • 10
    • 3
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human NERP2
    Isotype
    IgG
  • Indications d'application
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C/-80 °C
    Stockage commentaire
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Date de péremption
    12 months
  • Antigène
    NERP-2 (Neuroendocrine Regulatory Peptide 2 (NERP-2))
    Autre désignation
    VGF/NERP2 (NERP-2 Produits)
    Synonymes
    anticorps Gm1052, anticorps VGF nerve growth factor inducible, anticorps VGF, anticorps Vgf
    Sujet

    This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. Nerve growth factor (NGF) is a peptide that plays a key role in the differentiation and survival of neurons in the peripheral nervous system (PNS) and the central nervous system (CNS). VGF is a peptide synthesized and secreted by neurons and is upregulated by NGF in the PC12 cell line. VGF is widely expressed in both the PNS and CNS, but is especially abundant in the adult hypothalamus. VGF plays an essential role in how the brain regulates energy expenditure and body weight. Its expression is rapidly induced by injury, the circadian clock, and neuronal activity.

    Subcellular location: Cytoplasm, Secreted

    Synonyms: NERP-2, Nerve growth factor inducible, Neuroendocrine regulatory peptide-2, Neurosecretory protein VGF, VGF, VGF_HUMAN.

    ID gène
    7425
    UniProt
    O15240
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