PLAG1 anticorps (AA 51-150) (HRP)

N° du produit ABIN1712377

Cet anticorps Lapin Polyclonal détecte spécifiquement PLAG1 dans WB et ELISA. Il présente une réactivité envers Souris.

Aperçu rapide pour PLAG1 anticorps (AA 51-150) (HRP) (ABIN1712377)

Antigène: PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLAG1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA

Détail du produit anti-PLAG1 anticorps (HRP)

Épitope: AA 51-150

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PLAG1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-1000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Gentamicin sulfate

Précaution d'utilisation: This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PLAG1

Antigène: PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))

Autre désignation: PLAG1

Sujet:

Synonyms: PSA, SGPA, ZNF912, Zinc finger protein PLAG1, Pleiomorphic adenoma gene 1 protein, PLAG1

Background: Transcription factor whose activation results in up-regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation: when overexpressed in cultured cells, higher proliferation rate and transformation are observed. Other target genes such as CRLF1, CRABP2, CRIP2, PIGF are strongly induced in cells with PLAG1 induction. Proto-oncogene whose ectopic expression can trigger the development of pleomorphic adenomas of the salivary gland and lipoblastomas. Overexpression is associated with up-regulation of IGFII, is frequently observed in hepatoblastoma, common primary liver tumor in childhood. Cooperates with CBFB-MYH11, a fusion gene important for myeloid leukemia.

ID gène: 5324

UniProt: Q6DJT9