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GOT1L1 anticorps (AA 201-300) (HRP)

GOT1L1 Reactivité: Souris, Rat WB, IHC (p), IHC (fro) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1712548
  • Antigène Tous les produits GOT1L1
    GOT1L1 (Glutamic-Oxaloacetic Transaminase 1-Like 1 (GOT1L1))
    Épitope
    • 14
    • 9
    • 8
    • 7
    AA 201-300
    Reactivité
    • 30
    • 14
    • 4
    Souris, Rat
    Hôte
    • 31
    Lapin
    Clonalité
    • 31
    Polyclonal
    Conjugué
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GOT1L1 est conjugé à/à la HRP
    Application
    • 18
    • 15
    • 14
    • 14
    • 13
    • 13
    • 7
    • 5
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human GOT1L1
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C/-80 °C
    Stockage commentaire
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Date de péremption
    12 months
  • Antigène
    GOT1L1 (Glutamic-Oxaloacetic Transaminase 1-Like 1 (GOT1L1))
    Autre désignation
    GOT1L1 (GOT1L1 Produits)
    Synonymes
    anticorps 1700083M11Rik, anticorps RGD1307172, anticorps glutamic-oxaloacetic transaminase 1 like 1, anticorps glutamic-oxaloacetic transaminase 1-like 1, anticorps GOT1L1, anticorps Got1l1
    Sujet

    GOT1L1, Glutamate oxaloacetate transaminase 1-like protein 1, is a 421 amino acid member of the class-I pyridoxal-phosphate-dependent aminotransferase family. Similar to glutamate-oxaloacetate transaminase (GOT1), GOT1L1 is found primarily as a homodimer in the cytoplasmic space but also has mitochondrial and chloroplastic isozymes. GOT1L1 transaminates 2-oxoglutarate with L-aspartate to yield oxaloacetate and L-glutamate. This reaction requires a pyridoxal phosphate cofactor to occur. The GOT1L1 peptidase is predominately expressed in the liver and serum levels of this protein can be used as an indicator of liver disease. Also, elevated glutamate concentrations in the brain interstitial fluids can lead to pathological brain conditions. The glutamate-scavenging properties of these aminotranferase type enzymes likely prevent glutamate excitotoxicity and the long-lasting neurological deficits seen after stroke.

    Subcellular location: Cytoplasm

    Synonyms: AATC2_HUMAN, cytoplasmic 2, Glutamate oxaloacetate transaminase 1-like protein 1, Glutamic oxaloacetic transaminase 1 like 1, GOT1L1, Putative aspartate aminotransferase, Putative aspartate aminotransferase, cytoplasmic 2, Transaminase A-like protein 1.

    ID gène
    137362
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