Hepcidin 25 anticorps (AA 60-84) (HRP)

N° du produit ABIN1712656

Cet anticorps Lapin Polyclonal détecte spécifiquement Hepcidin 25 dans IHC (p). Il présente une réactivité envers Souris et Rat.

Aperçu rapide pour Hepcidin 25 anticorps (AA 60-84) (HRP) (ABIN1712656)

Antigène: Hepcidin 25 (HEPC25)

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Hepcidin 25 est conjugé à/à la HRP

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Hepcidin 25 anticorps (HRP)

Épitope: AA 60-84

Réactivité croisée: Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from rat Hepcidin

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Hepcidin 25

Antigène: Hepcidin 25 (HEPC25)

Autre désignation: Hepcidin 25

Sujet:

Synonyms: Hamp, HEPC, HEPC_RAT, HEPC_MOUSE, Hepc20, Hepc25, HEPCIDIN, Hepcidin, Hepcidin 20, Hepcidin 25, Hepcidin antimicrobial peptide, Hepcidin-20, Hepcidin25, HFE2, HFE2B, LEAP 1, LEAP-1, LEAP1, Liver expressed antimicrobial peptide, Liver-expressed antimicrobial peptide 1, PLTR, Putative liver tumor regressor.

Background: The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Jul 2008].

ID gène: 84604

UniProt: Q99MH3