BOC anticorps (PE)

N° du produit ABIN1712708

L’anticorps Lapin Polyclonal anti-BOC a été validé pour FACS. Il convient pour détecter BOC dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour BOC anticorps (PE) (ABIN1712708)

Antigène: BOC (Brother Of CDO (BOC))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BOC est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-BOC anticorps (PE)

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Protein BOC

Isotype: IgG

Information d'application

Indications d'application: FCM: 1:20-100
Optimal working dilution should be determined by the investigator.

Commentaires:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at 4 °C

Date de péremption: 12 months

Détails sur BOC

Antigène: BOC (Brother Of CDO (BOC))

Autre désignation: Protein Boc

Sujet:

BOC is a receptor-like, single pass membrane protein belonging to the cell surface molecule subfamily of the Immunoglobulin/fibronectin type-III repeat family within the immunoglobulin superfamily. It contains three fibronectin type-III domains and four Immunoglobulin-like C2-type domains in its extracellular region. The intracellular region of BOC is not required for proper function. BOC localizes to the cell membrane and is ubiquitously expressed with highest expression levels in skeletal muscle and small intestine. Its mRNA expression is down-regulated by Ras. BOC is involved in accelerating myoblast differentiation and is dependent on CDO for its activity. BOC and CDO are co-expressed in muscle precursors and are components of a receptor complex that mediates cell-cell interactions important in myogenesis. Overexpression of BOC results in enhanced differentiation of myoblast cells. In addition, BOC is a target and signaling component of the Shh pathway.

Subcellular location: Extracellular

Synonyms: Boc homolog mouse, Brother of CDO, Protein BOC, brother of CDO precursor, Protein BOC, BOC_HUMAN.

ID gène: 91653

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development