MEGF10 anticorps (PE)

N° du produit ABIN1712718

Cet anticorps anti-MEGF10 est un anticorps Lapin Polyclonal détectant MEGF10 dans IF (cc), IHC (fro) et IHC (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour MEGF10 anticorps (PE) (ABIN1712718)

Antigène: MEGF10 (Multiple EGF-Like-Domains 10 (MEGF10))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEGF10 est conjugé à/à la PE

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-MEGF10 anticorps (PE)

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MEGF10

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at 4 °C for 12 months.

Date de péremption: 12 months

Détails sur MEGF10

Antigène: MEGF10 (Multiple EGF-Like-Domains 10 (MEGF10))

Autre désignation: Megf10

Sujet: MEGF10 is a 1,140 amino acid protein encoded by the human gene MEGF10. MEGF10 belongs to the MEGF family and contains fifteen EGF-like domains and one EMI domain. The engulfment of dying cells is a specialized form of phagocytosis that is highly conserved across evolution and is mediated by the concerted action of several molecules. MEGF10 is an engulfment receptor protein that localizes to the plasma membrane in a punctuated pattern. The MEGF10 protein shares structural similarities with nematode engulfment receptor cell death abnormal-1 (CED-1). MEGF10 function is modulated by the ATP binding cassette transporter ABCA1, which is an ortholog to CED-7. It is expressed at the cell surface in clusters around cell corpses during engulfment, and during the engulfment of apoptotic thymocytes is recruited to the bottom of the forming phagocytic cup.
Synonyms: MEG10_HUMAN, MEGF protein, megf10, Multiple EGF-like domains protein 10, multiple EGF-like-domains 10, Multiple epidermal growth factor-like domains 10, Multiple epidermal growth factor-like domains protein 10.
Subcellular locations: Extracellular

ID gène: 84466

Pathways: Regulation of Muscle Cell Differentiation