FXYD6 anticorps (PE-Cy5)

N° du produit ABIN1712962

Cet anticorps Lapin Polyclonal détecte spécifiquement FXYD6 dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour FXYD6 anticorps (PE-Cy5) (ABIN1712962)

Antigène: FXYD6 (FXYD Domain Containing Ion Transport Regulator 6 (FXYD6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FXYD6 est conjugé à/à la PE-Cy5

Application: Western Blotting (WB)

Détail du produit anti-FXYD6 anticorps (PE-Cy5)

Homologie: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FXYD6

Isotype: IgG

Information d'application

Indications d'application: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur FXYD6

Antigène: FXYD6 (FXYD Domain Containing Ion Transport Regulator 6 (FXYD6))

Autre désignation: FXYD6

Sujet:

Synonyms: FXYD domain containing ion transport regulator 6, FXYD domain containing ion transport regulator 6 precursor, Phosphohippolin, UNQ521/PRO1056, FXYD6_HUMAN.

Background: The mammalian FXYD family maintains Na+ and K+ gradients between the intracellular and extracellular milieus of cells in processes such as renal Na+-reabsorption, muscle contraction and neuronal excitability. FXYDs are single-span membrane proteins that share a 35 amino acid signature domain, beginning with the sequence PFXYD and containing seven invariant and six conserved amino acids. Members of the FXYD family include FXYD1 (PLM, phospholemman), FXYD2 (the g subunit of the Na+/K+-ATPase), FXYD3 (Mat8, mammary tumor protein), FXYD4 (CHIF) and FXYD5 (RIC). FXYD6 is expressed in various epithelial cells bordering the endolymph space and in the auditory neurons. FXYD6 co-localizes with Na+/K+-ATPase in the stria vascularis and can be co-immunoprecipitated with Na+/K+-ATPase. After expression, FXYD6 associates with Na+/K+-ATPase alpha1-beta1 and alpha1-beta2 isozymes, which are preferentially expressed in different regions of the inner ear and also with gastric and non-gastric H+/K+-ATPase.

ID gène: 53826