PTCHD2 anticorps (PE-Cy7)

N° du produit ABIN1713255

Cet anticorps anti-PTCHD2 est un anticorps Lapin Polyclonal détectant PTCHD2 dans WB. Adapté pour Humain, Souris, Rat, Poulet, Boeuf (Vache), Chien et Porc.

Aperçu rapide pour PTCHD2 anticorps (PE-Cy7) (ABIN1713255)

Antigène: PTCHD2 (Patched Domain Containing 2 (PTCHD2))

Reactivité: Humain, Souris, Rat, Poulet, Boeuf (Vache), Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTCHD2 est conjugé à/à la PE-Cy7

Application: Western Blotting (WB)

Détail du produit anti-PTCHD2 anticorps (PE-Cy7)

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PTCHD2/DISP3

Isotype: IgG

Information d'application

Indications d'application: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PTCHD2

Antigène: PTCHD2 (Patched Domain Containing 2 (PTCHD2))

Autre désignation: PTCHD2/DISP3

Sujet:

Synonyms: DISP3, Dispatched, drosophila, homolog of, 3, G630052C06Rik, hCG_24779, KIAA1337, Patched domain-containing protein 2, Protein dispatched homolog 3, Ptchd2, PTHD2_HUMAN, RGD1305820, RND-type protein RNDEu-2, RNDEu-2, patched domain containing 2, RP23-157B15.1.

Background: PTCHD2 is a 1,392 amino acid multi-pass membrane protein that contains one SSD (sterol-sensing) domain and belongs to the patched family. Expressed in retina, brain and testis, PTCHD2 localizes to endoplasmic reticulum and colocalizes with cholesterol. PTCHD2 overexpression leads to increased cholesterol levels, suggesting that PTCHD2 may play a role in cholesterol homeostasis. PTCHD2 is further hypothesized to act as a link between thyroid hormone and cholesterol metabolism. Existing as two alternatively spliced isoforms, PTCHD2 is thought to assist in the release of lipid-anchored secreted proteins and is encoded by a gene that maps to human chromosome 1p36.22.

ID gène: 57540