APOL1 anticorps (AA 201-300)

N° du produit ABIN1713364

Cet anticorps Lapin Polyclonal détecte spécifiquement APOL1 dans WB, ELISA, IHC (p), IF (cc), IF (p), ICC et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour APOL1 anticorps (AA 201-300) (ABIN1713364)

Antigène: APOL1 (Apolipoprotein L, 1 (APOL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APOL1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-APOL1 anticorps

Épitope: AA 201-300

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human APOL1/Apolipoprotein L

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur APOL1

Antigène: APOL1 (Apolipoprotein L, 1 (APOL1))

Autre désignation: APOL1/Apolipoprotein L

Sujet:

Synonyms: APO L, Apo-L, APOL, APOL I, ApoL-I, APOL1, Apolipoprotein L1, APOL1_HUMAN, APOLI, APOL1, APOL 1, APOL-1, Apolipoprotein L, Apolipoprotein L I, Apolipoprotein L-I, Apolipoprotein L1, Apolipoprotein L-1, FSGS4.

Background: Apolipoproteins are protein components of plasma lipoproteins (1). The apolipoprotein L gene family encodes six highly homologous proteins designated apoL-I to -VI, which are associated with large high density type lipoproteins (HDL) (2,3). The human apoL family maps to chromosome 22q12.1-13.1 within a 127,000-bp region (4). ApoL has been characterized as a pancreas specific, 383-amino acid protein that contains a 12-amino acid secretory signal peptide (4). The apoL genes have TATA-less promoters and contain putative sterol regulatory elements, suggesting that transcription of these genes may be coordinated with that of the low density lipoprotein receptor and genes in pathways involving the synthesis of triglycerides and cholesterol (3). ApoL homologs can undergo 10 fold changes in expression during atherosclerotic changes in vascular endothelial cells, which includes the inflammatory reaction of atherosclerotic lesions (5).

ID gène: 8542