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C1ORF146 anticorps (AA 41-140)

C1ORF146 Reactivité: Humain WB, IF (cc), IF (p), ELISA, IHC (fro), IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1713381
  • Antigène Tous les produits C1ORF146
    C1ORF146 (Chromosome 1 Open Reading Frame 146 (C1ORF146))
    Épitope
    • 14
    • 2
    • 1
    AA 41-140
    Reactivité
    • 19
    • 4
    • 3
    Humain
    Hôte
    • 20
    Lapin
    Clonalité
    • 20
    Polyclonal
    Conjugué
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp C1ORF146 est non-conjugé
    Application
    • 20
    • 12
    • 12
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Homologie
    Human
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human C1orf146
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    C1ORF146 (Chromosome 1 Open Reading Frame 146 (C1ORF146))
    Autre désignation
    C1orf146 (C1ORF146 Produits)
    Synonymes
    anticorps RP11-163M2.4, anticorps chromosome 1 open reading frame 146, anticorps C1orf146
    Sujet

    Synonyms: C1orf146, CA146_HUMAN, Chromosome 1 open reading frame 146, RP11-163M2.3, RP11-163M2.4, Uncharacterized protein C1orf146.

    Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf146 gene product has been provisionally designated C1orf146 pending further characterization.

    ID gène
    388649
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