CEP57 anticorps (AA 51-150)

N° du produit ABIN1713745

Cet anticorps Lapin Polyclonal détecte spécifiquement CEP57 dans ELISA, IF (cc), IF (p), IHC (p), ICC et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour CEP57 anticorps (AA 51-150) (ABIN1713745)

Antigène: CEP57 (Centrosomal Protein 57kDa (CEP57))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CEP57 est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-CEP57 anticorps

Épitope: AA 51-150

Homologie: Human,Mouse,Rat,Dog,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CEP57

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur CEP57

Antigène: CEP57 (Centrosomal Protein 57kDa (CEP57))

Autre désignation: CEP57

Sujet:

Synonyms: Centrosomal protein 57 kDa, Centrosomal protein of 57 kDa, Cep57, Cep57 protein, CEP57_HUMAN, FGF2 interacting protein, FGF2-interacting protein, KIAA0092, MVA2, PIG8, proliferation inducing protein 8, Testis specic protein 57, Testis-specic protein 57, Translokin, TSP57.

Background: CEP57 (centrosomal protein 57 kDa), also known as PIG8, TSP57 or Translokin, is a 500 amino acid protein that localizes to both the nucleus and the cytoplasm, specifically associating with microtubules at the centrosome. Expressed ubiquitously, CEP57 exists as a homodimer that functions to mediate the mitogenic activity and nuclear translocation of FGF-2, an internalized growth factor, thereby regulating FGF-2 signaling pathways. Additionally, CEP57 is thought to play a role in spermatogenesis, possibly via the indirect regulation of gene expression. Human CEP57 shares 88 % sequence identity with its mouse and bovine orthologs, suggesting a highly conserved role between species. Multiple isoforms of CEP57 exist due to alternative splicing events.

Pathways: M Phase, Maintenance of Protein Location, Protein targeting to Nucleus, Growth Factor Binding