Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Chloride Channel 5 anticorps (AA 1-100)

CLCN5 Reactivité: Humain ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1713746
  • Antigène Voir toutes Chloride Channel 5 (CLCN5) Anticorps
    Chloride Channel 5 (CLCN5)
    Épitope
    • 15
    • 14
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reactivité
    • 49
    • 14
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 49
    • 1
    Lapin
    Clonalité
    • 50
    Polyclonal
    Conjugué
    • 15
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Chloride Channel 5 est non-conjugé
    Application
    • 24
    • 20
    • 12
    • 12
    • 4
    • 2
    • 2
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Chloride Channel 5/CLC5
    Isotype
    IgG
  • Indications d'application
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Chloride Channel 5 (CLCN5)
    Autre désignation
    Chloride Channel 5 (CLCN5 Produits)
    Synonymes
    anticorps CLCN3, anticorps CLCN5, anticorps clcn5-A, anticorps DKFZp469O2315, anticorps 5430408K11Rik, anticorps ClC-5, anticorps Clc5, anticorps D930009B12Rik, anticorps DXImx42e, anticorps Sfc13, anticorps T25545, anticorps CLC5, anticorps CLCK2, anticorps DENTS, anticorps NPHL1, anticorps NPHL2, anticorps XLRH, anticorps XRN, anticorps hCIC-K2, anticorps CLCN4, anticorps Clcn5, anticorps chloride voltage-gated channel 5, anticorps chloride channel, voltage-sensitive 5 L homeolog, anticorps chloride channel, voltage-sensitive 5, anticorps CLCN5, anticorps clcn5.L, anticorps clcn5, anticorps Clcn5
    Sujet

    The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport and maintain cellular volume. The genes encoding human CLC-1 through CLC-7 map to chromosomes 7q32, 3q28, 4q32, Xp22.3, Xp11.23-p11.22, 1p36 and 16p13, respectively. CLC1 is highly expressed in skeletal muscle. Mutations in the gene encoding CLC1 lead to myotonia, an inheritable disorder characterized by muscle stiffness and renal salt wasting. CLC2 is highly expressed in the epithelia of several organs including lung, which suggests CLC2 may be a possible therapeutic target for cystic fibrosis. CLC3 expression is particularly abundant in neuronal tissue, while CLC4 expression is evident in skeletal and cardiac muscle as well as brain. Mutations in the gene encoding CLC5 lead to Dent?s disease, a renal disorder characterized by proteinuria and hypercalciuria. CLC6 and CLC7 are broadly expressed in several tissues including testis, kidney, brain and muscle.

    Subcellular location: Cytoplasm, Cell membrane

    Synonyms: Chloride channel protein 5, Chloride transporter ClC-5, ClC-5, CLC5, CLCK2, CLCN5, CLCN5_HUMAN, DENTS, H+/Cl- exchange transporter 5, hCIC-K2, NPHL1, NPHL2, XLRH, XRN.

Vous êtes ici:
Support technique