Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

GAMT anticorps (AA 101-200)

GAMT Reactivité: Humain WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1713803
  • Antigène Voir toutes GAMT Anticorps
    GAMT (Guanidinoacetate N-Methyltransferase (GAMT))
    Épitope
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    Reactivité
    • 24
    • 21
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 38
    • 2
    Lapin
    Clonalité
    • 39
    • 1
    Polyclonal
    Conjugué
    • 21
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp GAMT est non-conjugé
    Application
    • 22
    • 10
    • 7
    • 5
    • 4
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Mouse,Rat,Dog,Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human GAMT
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    GAMT (Guanidinoacetate N-Methyltransferase (GAMT))
    Autre désignation
    GAMT (GAMT Produits)
    Synonymes
    anticorps gamt, anticorps zgc:123136, anticorps CCDS2, anticorps PIG2, anticorps TP53I2, anticorps AA571402, anticorps Spintz1, anticorps MGC75698, anticorps GAMT, anticorps GMT, anticorps guanidinoacetate N-methyltransferase L homeolog, anticorps guanidinoacetate N-methyltransferase S homeolog, anticorps guanidinoacetate N-methyltransferase, anticorps guanidinoacetate methyltransferase, anticorps gamt.L, anticorps gamt.S, anticorps gamt, anticorps GAMT, anticorps Gamt
    Sujet

    In the creatine biosynthesis pathway, glycine is converted to guanidinoacetate by amidinotransferase, and guanidinoacetate is then converted to creatine by Guanidinoacetate N-methyltransferase (GAMT). GAMT, a methyltransferase, uses S-adenosylmethionine as the methyl donor for this reaction. Methyltransferases are a type of transferase enzyme which transfers a methyl group to nucleic bases in DNA or amino acids in protein. Encoding a 236 amino acid protein, the human GAMT gene maps to chromosome 19p13.3. Defects in the GAMT gene leads to GAMT deficiency, which is associated with guanidinoacetate accumulation and decreased levels of creatine excretion in brain. Such biochemical changes are thought to lead to various neurological syndromes and muscular hypotonia.

    Subcellular location: Cytoplasm, Nucleus

    Synonyms: PIG2, CCDS2, TP53I2, HEL-S-20, Guanidinoacetate N-methyltransferase, GAMT

    ID gène
    2593
    UniProt
    Q14353
Vous êtes ici:
Support technique