GAMT anticorps (AA 101-200)

N° du produit ABIN1713803

Détail du produit anti-GAMT anticorps

Antigène: GAMT (Guanidinoacetate N-Methyltransferase (GAMT))

Épitope: AA 101-200

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GAMT est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GAMT

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur GAMT

Antigène: GAMT (Guanidinoacetate N-Methyltransferase (GAMT))

Autre désignation: GAMT (GAMT Produits)

Synonymes: anticorps gamt, anticorps zgc:123136, anticorps CCDS2, anticorps PIG2, anticorps TP53I2, anticorps AA571402, anticorps Spintz1, anticorps MGC75698, anticorps GAMT, anticorps GMT, anticorps guanidinoacetate N-methyltransferase L homeolog, anticorps guanidinoacetate N-methyltransferase S homeolog, anticorps guanidinoacetate N-methyltransferase, anticorps guanidinoacetate methyltransferase, anticorps gamt.L, anticorps gamt.S, anticorps gamt, anticorps GAMT, anticorps Gamt

Sujet:

Synonyms: PIG2, CCDS2, TP53I2, HEL-S-20, Guanidinoacetate N-methyltransferase, GAMT

Background: In the creatine biosynthesis pathway, glycine is converted to guanidinoacetate by amidinotransferase, and guanidinoacetate is then converted to creatine by Guanidinoacetate N-methyltransferase (GAMT). GAMT, a methyltransferase, uses S-adenosylmethionine as the methyl donor for this reaction. Methyltransferases are a type of transferase enzyme which transfers a methyl group to nucleic bases in DNA or amino acids in protein. Encoding a 236 amino acid protein, the human GAMT gene maps to chromosome 19p13.3. Defects in the GAMT gene leads to GAMT deficiency, which is associated with guanidinoacetate accumulation and decreased levels of creatine excretion in brain. Such biochemical changes are thought to lead to various neurological syndromes and muscular hypotonia.

ID gène: 2593

UniProt: Q14353