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GART anticorps (AA 281-380)

GART Reactivité: Humain IF (cc), IF (p), ELISA, IHC (p), IHC (fro), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1713804
  • Antigène Tous les produits GART
    GART (Phosphoribosylglycinamide Formyltransferase (GART))
    Épitope
    • 14
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 281-380
    Reactivité
    • 46
    • 22
    • 10
    • 2
    Humain
    Hôte
    • 43
    • 4
    Lapin
    Clonalité
    • 36
    • 11
    Polyclonal
    Conjugué
    • 19
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GART est non-conjugé
    Application
    • 18
    • 13
    • 12
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Homologie
    Human,Mouse,Rat,Dog,Cow,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human GART
    Isotype
    IgG
  • Indications d'application
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    GART (Phosphoribosylglycinamide Formyltransferase (GART))
    Autre désignation
    GART (GART Produits)
    Synonymes
    anticorps Gaps, anticorps Prgs, anticorps AIRS, anticorps GARS, anticorps GART-A, anticorps gart, anticorps phosphoribosylglycinamide formyltransferase, anticorps phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase, anticorps phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase L homeolog, anticorps Gart, anticorps GART, anticorps gart.L
    Sujet

    Purines are critical for energy metabolism, cell signaling and cell reproduction and also function as precursors for coenzymes, energy transfer molecules, regulatory factors and proteins involved in RNA and DNA synthesis. GART (GAR transformylase), also referred to as AIRS, GARS, PAIS, PGFT, PRGS or GARTF, is 1,010 amino acids in length and is a key folate-dependent trifunctional enzyme with phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase and AICAR (phosphoribosylaminoimidazole synthetase) activity required for de novo purine biosynthesis. Cancer cells require considerable amounts of purines to sustain their accelerated growth and GART is, therefore, a target for cancer chemotherapy. GART is highly conserved in vertebrates. Two isoforms of GART are expressed due to alternative splicing events.

    Subcellular location: Cytoplasm

    Synonyms: 5'-phosphoribosylglycinamide transformylase, AIR synthase, AIRS, GAR transformylase, GARS, GART, GART, GARTF, Glycinamide ribonucleotide synthetase, MGC47764, PAIS, PGFT, Phosphoribosyl-aminoimidazole synthetase, Phosphoribosylglycinamide formyltransferase, Phosphoribosylglycinamide formyltransferase phosphoribosylglycinamide synthetase phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide formyltransferase, EC 2.1.2.29, Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide synthetase, PRGS, PUR2_HUMAN, Trifunctional purine biosynthetic protein adenosine 3.

    ID gène
    2618
    UniProt
    P22102
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