ARFGAP3 anticorps (AA 412-516)
Aperçu rapide pour ARFGAP3 anticorps (AA 412-516) (ABIN1714037)
Antigène
Voir toutes ARFGAP3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 412-516
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Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Chicken
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human ARFGAP3
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- ARFGAP3 (ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))
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Autre désignation
- ARFGAP3
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Sujet
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Synonyms: ADP ribosylation factor GTPase activating protein 1, ADP ribosylation factor GTPase activating protein 3, ADP-ribosylation factor GTPase-activating protein 3, ARF GAP 3, ARFG3_HUMAN, ArfGAP 3, ARFGAP1, ARFGAP3, FLJ45618.
Background: ARFGAP1 (ADP-ribosylation factor GTPase-activating protein 1), ARFGAP2 (ADP-ribosylation factor GTPase-activating protein 2) and ARFGAP3 (ADP-ribosylation factor GTPase-activating protein 3) are GTPase-activating proteins (GAP) that are associated with the Golgi apparatus and interact with ADP-ribosylation factor 1 (ARF). These proteins promote hydrolysis of ARF-bound GTP and are required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of ARFGAP1, ARFGAP2 and ARFGAP3 is stimulated by phosphoinosides and inhibited by phosphatidylcholine. The genes encoding ARFGAP1, ARFGAP2 and ARFGAP3 map to human chromosomes 20q13.33, 11p11.2 and 22q13.2, respectively.
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ID gène
- 26286
Antigène
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