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GEMIN7 anticorps (AA 21-120)

GEMIN7 Reactivité: Humain, Rat ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1714054
  • Antigène Voir toutes GEMIN7 Anticorps
    GEMIN7 (Gem (Nuclear Organelle) Associated Protein 7 (GEMIN7))
    Épitope
    • 15
    • 9
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    Reactivité
    • 38
    • 16
    • 10
    • 1
    • 1
    • 1
    • 1
    Humain, Rat
    Hôte
    • 34
    • 4
    Lapin
    Clonalité
    • 35
    • 3
    Polyclonal
    Conjugué
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GEMIN7 est non-conjugé
    Application
    • 13
    • 12
    • 12
    • 12
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Homologie
    Mouse,Dog,Cow,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Gemin 7
    Isotype
    IgG
  • Indications d'application
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    GEMIN7 (Gem (Nuclear Organelle) Associated Protein 7 (GEMIN7))
    Autre désignation
    Gemin 7 (GEMIN7 Produits)
    Synonymes
    anticorps SIP3, anticorps GEMIN7, anticorps Gemin7, anticorps 2400008I04Rik, anticorps AI120175, anticorps AI461688, anticorps gem nuclear organelle associated protein 7, anticorps gem (nuclear organelle) associated protein 7, anticorps GEMIN7, anticorps Gemin7
    Sujet

    Gemin7 is a 131 amino acid protein encoded by the mouse gene Gemin7. Gemin7, along with Gemin6, is a significant component of the the large multiprotein human SMN complex. The SMN complex functions as an assembly machine for small nuclear ribonucleoproteins (snRNPs)-the major components of the spliceosome. The survival of motor neurons (SMN) protein, a product of the disease gene of the common neurodegenerative disease, spinal muscular atrophy, is also part of the SMN complex. Although Gemin6 and Gemin7 have no significant sequence similarity with Sm proteins, both adopt canonical Sm folds. Moreover, Gemin6 and Gemin7 exist as a heterodimer, and interact with each other via an interface similar to that which mediates interactions among the Sm proteins. The Gemin6/Gemin7 complex binds to Sm proteins and might help organize Sm proteins for formation of Sm rings on snRNA targets.

    Subcellular location: Nucleus

    Synonyms: SIP3, Gemin7, Gemin-7, GEMI7_HUMAN.

    ID gène
    79760
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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