GSK3 alpha/beta anticorps (AA 151-250)

N° du produit ABIN1714094

Détail du produit anti-GSK3 alpha/beta anticorps

Antigène: GSK3 alpha/beta (GSK3a/b) (Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b))

Épitope: AA 151-250

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSK3 alpha/beta est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GSK3 Alpha + Beta

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-GSK3 alpha/beta (ABIN1714094)

Freese, Reinhardt, Hefner, Unger, Kirkpatrick, Endres: "A novel blood-brain barrier co-culture system for drug targeting of Alzheimer's disease: establishment by using acitretin as a model drug." dans: PLoS ONE, Vol. 9, Issue 3, pp. e91003, (2014) (PubMed).

Détails sur GSK3 alpha/beta

Antigène: GSK3 alpha/beta (GSK3a/b) (Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b))

Autre désignation: GSK3 Alpha + Beta (GSK3a/b Produits)

Sujet:

Synonyms: Gsk3a, GSK 3 alpha, GSK-3 alpha, GSK3 alpha, Glycogen synthase kinase-3 alpha, GSK 3 alpha, DKFZp686D0638, GSK 3A, GSK3A, GSK3alpha, GSK3A_HUMAN, Glycogen synthase kinase 3 alpha, Serine/threonine-protein kinase GSK3A, Glycogen synthase kinase 3 beta, GSK 3 beta, GSK 3B, GSK3B, GSK3B protein, GSK3beta isoform, GSK3 beta, Glycogen synthase kinase-3 beta, GSK-3 beta, GSK3B_HUMAN, Serine/threonine-protein kinase GSK3B.

Background: The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009].