Dymeclin anticorps (AA 151-250)
Aperçu rapide pour Dymeclin anticorps (AA 151-250) (ABIN1714524)
Antigène
Voir toutes Dymeclin (DYM) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 151-250
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Réactivité croisée
- Humain, Rat
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Homologie
- Mouse,Dog,Cow,Sheep,Horse
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human Dymeclin
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- Dymeclin (DYM)
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Autre désignation
- Dymeclin
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Sujet
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Synonyms: DMC, Dyggve-Melchior-Clausen syndrome protein, DYM, FLJ20071, FLJ90130, SMC, DYM_HUMAN.
Background: Dyggve-Melchior-Clausen syndrome (DMC), a rare autosomal recessive disorder, is characterized by microcephaly, short trunk dwarfism and sometime psychomotor retardation. Cutaneous cells of affected individuals show dilated rough endoplasmic reticulum and enlarged vacuoles. The Dyggve-Melchior-Clausen syndrome protein, also designated dymeclin, may play a role in proteoglycan metabolism and intracellular protein digestion. It is a widely expressed multi-pass membrane protein, detected primarily in chondrocytes and fetal brain tissue. Defects in dymeclin are also the cause of Smith-McCort dysplasis syndrome (SMC), which has characteristics identical to those of Dyggve-Melchior-Clausen syndrome.
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ID gène
- 54808
Antigène
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