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FMN1 anticorps (AA 651-750)

FMN1 Reactivité: Humain, Rat WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1714537
  • Antigène Voir toutes FMN1 Anticorps
    FMN1 (Formin 1 (FMN1))
    Épitope
    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 651-750
    Reactivité
    • 25
    • 15
    • 2
    Humain, Rat
    Hôte
    • 23
    • 3
    Lapin
    Clonalité
    • 25
    • 1
    Polyclonal
    Conjugué
    • 9
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FMN1 est non-conjugé
    Application
    • 22
    • 12
    • 12
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
     Réactivité croisée
    Humain, Rat
    Homologie
    Mouse,Dog,Cow,Sheep
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human FMN1/Formin 1
    Isotype
    IgG
    Top Product
    Discover our top product FMN1 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    FMN1 (Formin 1 (FMN1))
    Autre désignation
    FMN1/Formin 1 (FMN1 Produits)
    Synonymes
    anticorps si:dkey-81b15.10, anticorps fmn, anticorps formin, anticorps FMN, anticorps LD, anticorps BB164513, anticorps Fmn, anticorps formin-1, anticorps ld, anticorps RGD1306349, anticorps RGD1310100, anticorps formin 1, anticorps fmn1, anticorps FMN1, anticorps Fmn1
    Sujet

    Synonyms: FMN, Formin 1, Formin1, Formin-1, LD, Limb deformity protein homolog, FMN1_HUMAN.

    Background: The temporal genetic hierarchy influencing normal limb development can deregulate and mediate mammalian developmental syndromes. In mice, the limb deformity (ld) locus influences normal limb development and gives rise to alternative mRNAs that can translate into a family of proteins known as formins. Formins play a crucial role in cytoskeletal reorganization by influencing Actin filament assembly. Formins co-localize with the actin cytoskeleton and can translocate into the cell cytosol and into the nucleus in an HGF-dependent manner. Vertebrate nuclear formins can control polarizing activity in limb buds through establishment of a Sonic hedgehog/FGF-4 feedback loop. Deficiency mutations at the mammalian ld locus lead to profound developmental defects in limb and kidney formation. The human Formin 1 and 2 genes map to chromosome 15q13.3 and 1q43, respectively.

    ID gène
    342184
    Pathways
    Regulation of Actin Filament Polymerization
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