Glutathione Peroxidase 2 anticorps (AA 41-140)

N° du produit ABIN1714555

Cet anticorps Lapin Polyclonal détecte spécifiquement Glutathione Peroxidase 2 dans ELISA, WB, ICC, IHC (p), IF (cc), IF (p) et IHC (fro). Il présente une réactivité envers Souris.

Aperçu rapide pour Glutathione Peroxidase 2 anticorps (AA 41-140) (ABIN1714555)

Antigène: Glutathione Peroxidase 2 (GPX2)

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutathione Peroxidase 2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Glutathione Peroxidase 2 anticorps

Épitope: AA 41-140

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GPX2/Glutathione Peroxidase 2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Glutathione Peroxidase 2

Antigène: Glutathione Peroxidase 2 (GPX2)

Autre désignation: GPX2/Glutathione Peroxidase 2

Sujet:

Synonyms: Gastrointestinal glutathione peroxidase, GI GPx, Glutathione peroxidase 2 gastrointestinal, Glutathione peroxidase 2, Glutathione peroxidase gastrointestinal, Glutathione peroxidase related protein 2, Glutathione peroxidase-gastrointestinal, Glutathione peroxidase-related protein 2, GPRP, GPRP-2, GPx 2, GPx-2, GPx-GI, GPX2, GPX2_HUMAN, GSHPx 2, GSHPx GI, GSHPx-2, GSHPx-GI.

Background: Glutathione peroxidase (GPx) enzymes are generally selenium-containing tetrameric glycoproteins that help prevent lipid peroxidation of cell membranes. GPx enzymes reduce lipid hydroperoxides to alcohols, and reduce free hydrogen peroxide to water. GPx members are among the few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. There are eight GPx homologs (GPx-18). GPx-1 plays an important role in the antioxidant defense of the vascular wall and neural cells in response to oxidative stress. GPx-2 is the major isoform in the lungs and its basal or inducible expression is dependent on Nrf2. GPx-3 is under regulation by hypoxic stress and the expression and deficiency of GPx-3 is associated with cardiovascular disease and stroke. GPx-5 is selenium-independent, it is bound to the acrosome of sperm, where it may protect sperm from premature acrosome reaction in the epididymis.

ID gène: 2877

Pathways: Thyroid Hormone Synthesis