PIP5KL1 anticorps (AA 101-220)
Aperçu rapide pour PIP5KL1 anticorps (AA 101-220) (ABIN1714568)
Antigène
Voir toutes PIP5KL1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 101-220
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Réactivité croisée
- Souris, Rat
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Homologie
- Human,Dog,Cow,Horse,Rabbit
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human PIP5KL1/PIPKH
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Isotype
- IgG
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Indications d'application
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- PIP5KL1 (Phosphatidylinositol-4-Phosphate 5-Kinase-Like 1 (PIP5KL1))
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Autre désignation
- PIP5KL1
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Sujet
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Synonyms: bA203J24.5, EC 2.7.1.68, MGC46424, phosphatidylinositol 4 phosphate 5 kinase like 1, phosphatidylinositol phosphate kinase homolog, Phosphatidylinositol-4-phosphate 5-kinase-like protein 1, PI4P 5 kinase like protein 1, PI4P 5-kinase-like protein 1, PI5L1_HUMAN, PIP5KL1, PIPKH, PtdIns4P 5 kinase like protein 1, PtdIns4P-5-kinase-like protein 1.
Background: PIPKH, also known as PIP5KL1 (phosphatidylinositol-4-phosphate 5-kinase-like 1), is a 394 amino acid phosphoinositide kinase-like protein that contains one PIPK domain. Although PIPKH lacks intrinsic lipid kinase activity, it associates with type I PIPKs and may play a role in localization of PIPK activity. Encoded by a gene that maps to human chromosome 9q34.11, PIPKH localizes to cytoplasm, specifically to large cytoplasmic vesicular structures, and exists as two alternatively spliced isoforms. Highly expressed in brain and testis, PIPKH is also expressed at very low levels in heart, spleen, lung, liver, skeletal muscle and kidney. PIPKH heterodimerizes with other type I phosphatidylinositol-4-phosphate 5-kinases, and may function as a scaffold to localize and regulate kinases to specific cell compartments. Overexpression of PIPKH may suppress cell proliferation and migration in human gastric cancer cells and may also inhibit cervical cancer formation.
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ID gène
- 138429
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Pathways
- Inositol Metabolic Process
Antigène
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