FOSB anticorps (pSer27)
Aperçu rapide pour FOSB anticorps (pSer27) (ABIN1714584)
Antigène
Voir toutes FOSB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer27
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Réactivité croisée
- Humain
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Homologie
- Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Guinea Pig
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic phosphopeptide derived from human Fos B around the phosphorylation site of Ser27
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))
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Autre désignation
- FosB
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Sujet
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Synonyms: Fos B phospho S27, p-Fos B phospho S27, p-FosB phospho S27, FBJ murine osteosarcoma viral oncogene homolog B, FOS B, FOS-B, FBJ osteosarcoma oncogene B, FosB, G0/G1 switch regulatory protein 3, G0S3, GOS3, GOSB, MGC42291, Oncogene FOS B, Protein fosB, fosB, G0/G1 switch regulatory protein 3, G0S3, GOS 3, GOS B, GOSB, Oncogene FOS B, Oncogene FOSB, Protein fos B, DKFZp686C0818, FOSB_HUMAN.
Background: The v-Fos oncogene was initially identified as the transforming gene of two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phosphoprotein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA TPA response elements (TREs), c-Fos proteins are only active as heterodimers with members of the Jun gene family. Murine Fos B encodes a nuclear protein of 338 amino acids which has 70 % homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos B include Fra-1 and Fra-2 genes.
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ID gène
- 2354
Antigène
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