FFAR1 anticorps (AA 121-220)

N° du produit ABIN1714627

Cet anticorps Lapin Polyclonal détecte spécifiquement FFAR1 dans WB, ELISA, IF (cc), IF (p), IHC (p), ICC et IHC (fro). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour FFAR1 anticorps (AA 121-220) (ABIN1714627)

Antigène: FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FFAR1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-FFAR1 anticorps

Épitope: AA 121-220

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GPR40

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur FFAR1

Antigène: FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

Autre désignation: GPR40

Sujet:

Synonyms: FFA1R, GPR40, GPCR40, Free fatty acid receptor 1, G-protein coupled receptor 40, FFAR1

Background: G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis, receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.

ID gène: 2864

UniProt: O14842

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis