PLAG1 anticorps (AA 51-150)

N° du produit ABIN1714862

L’anticorps Lapin Polyclonal anti-PLAG1 a été validé pour WB et ELISA. Il convient pour détecter PLAG1 dans des échantillons de Souris.

Aperçu rapide pour PLAG1 anticorps (AA 51-150) (ABIN1714862)

Antigène: PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLAG1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PLAG1 anticorps

Épitope: AA 51-150

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PLAG1

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur PLAG1

Antigène: PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))

Autre désignation: PLAG1

Sujet:

Synonyms: PSA, SGPA, ZNF912, Zinc finger protein PLAG1, Pleiomorphic adenoma gene 1 protein, PLAG1

Background: Transcription factor whose activation results in up-regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation: when overexpressed in cultured cells, higher proliferation rate and transformation are observed. Other target genes such as CRLF1, CRABP2, CRIP2, PIGF are strongly induced in cells with PLAG1 induction. Proto-oncogene whose ectopic expression can trigger the development of pleomorphic adenomas of the salivary gland and lipoblastomas. Overexpression is associated with up-regulation of IGFII, is frequently observed in hepatoblastoma, common primary liver tumor in childhood. Cooperates with CBFB-MYH11, a fusion gene important for myeloid leukemia.

ID gène: 5324

UniProt: Q6DJT9