FKBP3 anticorps (AA 31-130)

N° du produit ABIN1715006

L’anticorps anti-FKBP3 Polyclonal Lapin est utilisé pour la détection de FKBP3 dans des échantillons de Humain. Il a été validé pour WB, IHC (p), IF (cc), IF (p) et IHC (fro).

Aperçu rapide pour FKBP3 anticorps (AA 31-130) (ABIN1715006)

Antigène: FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FKBP3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-FKBP3 anticorps

Épitope: AA 31-130

Fonction: FKBP25 Polyclonal Antibody

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FKBP25

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000),

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur FKBP3

Antigène: FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))

Autre désignation: FKBP25

Sujet:

Synonyms: FKBP 25, FKBP 3, FKBP25, FKBP3, PPIase, Rotamase, FKBP3_HUMAN.

Background: FKBP25 is a member of the immunophilin protein family. The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs, such as cyclosporin, FK506 and rapamycin. They inhibit T-cell proliferation by interrupting two specific cytoplasmic signal transmission pathways. FKBP25 is localized in the nucleus and is expressed in the brain, testis, ovary, and spleen. It may influence immunoregulation and cerebellum development, as well as protein folding and trafficking in neurons. FKBP25 associates with transcriptional repressor protein YY1 and histone deaceltylases, HDAC1 and HDAC2. FKBP25 may contain several casein kinase II phosphorylation sites, which are believed to be important for cell growth regulation.

ID gène: 2287