SKAP1 anticorps (AA 101-200)

N° du produit ABIN1715089

Cet anticorps Lapin Polyclonal détecte spécifiquement SKAP1 dans ELISA, ICC, IHC (p), IF (cc), IF (p) et IHC (fro). Il présente une réactivité envers Rat.

Aperçu rapide pour SKAP1 anticorps (AA 101-200) (ABIN1715089)

Antigène: SKAP1 (Src Kinase Associated phosphoprotein 1 (SKAP1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SKAP1 est non-conjugé

Application: ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-SKAP1 anticorps

Épitope: AA 101-200

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SKAP55

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur SKAP1

Antigène: SKAP1 (Src Kinase Associated phosphoprotein 1 (SKAP1))

Autre désignation: SKAP55

Sujet:

Synonyms: pp55, SCAP 1, SCAP1, SKAP 1, SKAP 55, SKAP-55, Skap1, SKAP1_HUMAN, SKAP55 adaptor protein, SRC family associated phosphoprotein 1, Src family-associated phosphoprotein 1, Src kinase associated phosphoprotein 1, SRC kinase associated phosphoprotein 55 kD, Src kinase associated phosphoprotein of 55 kDa, Src kinase-associated phosphoprotein 1, Src kinase-associated phosphoprotein of 55 kDa.

Background: Fyb (Fyn binding protein) and the anchoring proteins SKAP55 and SKAP55-R (SKAP55-related protein) associate with the tyrosine kinase p59fyn. SKAP55 and SKAP55-R bind to Fyb through their SH3 domains and function as substrates for p59Fyn in resting T cells. SKAP55 contains an N-terminal pleckstrin homology domain and a C-terminal SH3 domain binding motif of adjacent arginine and lysine residues followed by tandem tyrosines. SKAP55-R, similar in overall structure to SKAP55, contains a coiled-coil N-terminal domain. SKAP55 associates with SLAP-130, another component of the Fyn complex, which plays a role in the regulation of signaling events initiated by lymphocyte antigen receptors leading up to T cell activation. The human SKAP55 gene maps to chromosome 17q21.32 and encodes a 359 amino acid protein.