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LGR4 anticorps

LGR4 Reactivité: Humain FACS, cELISA Hôte: Rat Monoclonal BBX-1H1 unconjugated
N° du produit ABIN1720913
  • Antigène Voir toutes LGR4 Anticorps
    LGR4 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4))
    Reactivité
    • 34
    • 13
    • 11
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 27
    • 4
    • 3
    Rat
    Clonalité
    • 27
    • 7
    Monoclonal
    Conjugué
    • 23
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp LGR4 est non-conjugé
    Application
    • 12
    • 10
    • 8
    • 7
    • 4
    • 4
    • 2
    • 1
    Flow Cytometry (FACS), Cell-ELISA (cELISA)
    Specificité
    Anti-human LGR4
    Aucune reactivité croisée
    Souris
    Attributs du produit
    Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
    Purification
    Protein G
    Immunogène
    genetic immunisation with cDNA encoding human LGR4
    Clone
    BBX-1H1
    Isotype
    IgG2a kappa
  • Indications d'application
    Flow cytometry: 1.2 µg/10^6 cells
    CELISA: 1:200 - 1:400
    For each application a titration should be performed to determine the optimal concentration.
    Commentaires

    Synonyms: GPR48

    Restrictions
    For Research Use only
  • Buffer
    PBS, pH 7.2
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C
    Stockage commentaire
    short term: 2 °C - 8 °C, long term: -20 °C
  • Antigène
    LGR4 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4))
    Autre désignation
    LGR4 (LGR4 Produits)
    Synonymes
    anticorps BNMD17, anticorps GPR48, anticorps 9130225G07, anticorps A330106J01Rik, anticorps A930009A08Rik, anticorps Gpr48, anticorps leucine rich repeat containing G protein-coupled receptor 4, anticorps leucine-rich repeat-containing G protein-coupled receptor 4, anticorps LGR4, anticorps Lgr4
    Sujet
    LGR4 (Leucine-rich repeat- containing G protein-coupled receptor 4, GPR48) belongs to the superfamily of G protein-coupled receptors (GPCRs). It is a 951 amino acid multi-pass membrane protein and has multiple N-terminal leucine-rich repeats, which are important for interaction with the glycoprotein ligands, and 7 transmembrane domains. LGR4 is highly expressed in the adult human pancreas but also with moderate levels of expression in placenta, kidney, brain and heart. LGR4 functions as an orphan receptor that may be involved in physiologic activities throughout the cell. It is overexpressed in various cancer types and is thought to enhance carcinoma invasiveness and metastasis, suggesting an important role in tumor progression.
    UniProt
    Q9BXB1
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