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CD81 anticorps

CD81 Reactivité: Humain FACS, cELISA Hôte: Rat Monoclonal QV-6A8-S3 unconjugated
N° du produit ABIN1720914
  • Antigène Voir toutes CD81 Anticorps
    CD81
    Reactivité
    • 119
    • 102
    • 40
    • 18
    • 17
    • 7
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 65
    • 61
    • 32
    • 14
    • 2
    • 1
    Rat
    Clonalité
    • 124
    • 45
    • 3
    Monoclonal
    Conjugué
    • 74
    • 20
    • 17
    • 16
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD81 est non-conjugé
    Application
    • 125
    • 80
    • 44
    • 41
    • 31
    • 29
    • 29
    • 27
    • 17
    • 15
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Cell-ELISA (cELISA)
    Specificité
    Anti-human CD81 (TAPA-1)
    Attributs du produit
    Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
    Purification
    Protein G
    Immunogène
    genetic immunisation with cDNA encoding human CD81
    Clone
    QV-6A8-S3
    Isotype
    IgG2b
    Top Product
    Discover our top product CD81 Anticorps primaire
  • Indications d'application
    Flow cytometry: 1.2 µg/10^6 cells
    ELISA: 1:200 - 1:400
    CELISA: 1:200 - 1:400
    For each application a titration should be performed to determine the optimal concentration.
    Commentaires

    Synonyms: TAPA-1

    Restrictions
    For Research Use only
  • Buffer
    PBS, pH 7.2
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C
    Stockage commentaire
    short term: 2 °C - 8 °C, long term: -20 °C
  • Fofana, Xiao, Thumann, Turek, Zona, Tawar, Grunert, Thompson, Zeisel, Baumert: "A novel monoclonal anti-CD81 antibody produced by genetic immunization efficiently inhibits Hepatitis C virus cell-cell transmission." dans: PLoS ONE, Vol. 8, Issue 5, pp. e64221, (2013) (PubMed).

  • Antigène
    CD81
    Autre désignation
    CD81 (CD81 Produits)
    Synonymes
    anticorps Tapa-1, anticorps Tapa1, anticorps Tspan28, anticorps CVID6, anticorps S5.7, anticorps TAPA1, anticorps TSPAN28, anticorps CD81 molecule, anticorps CD81 molecule b, anticorps CD81 antigen, anticorps Cd81 molecule, anticorps CD81, anticorps cd81b, anticorps Cd81
    Sujet
    CD81 (TAPA-1) belongs to the transmembrane 4 superfamily (tetraspanin family). CD81 is a widely expressed cell-surface protein that is characterized by the presence of four transmembranic domains, short N and C termini, a small extracellular loop (SEL) and a large extra-cellular loop (LEL). It is expressed on cells of hematopoietic, neuroectodermal and mesenchymal origin and plays a role in the regulation of cell development, cell-growth and signal transduction. CD81 plays a critical role in Hepatitis C Infection and is involved in HCV entry due to its ability to interact with virus' E1/E2 glycoproteins. CD81 is an essential HCV host factor as silencing of CD81 expression by CD81-specific monoclonal antibodies in hepatoma cells inhibits HCV entry.
    UniProt
    P60033
    Pathways
    Inositol Metabolic Process, Hepatitis C
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