ASPSCR1 anticorps

N° du produit ABIN1724649

Cet anticorps anti-ASPSCR1 est un anticorps Souris Monoclonal détectant ASPSCR1 dans WB et ELISA. Adapté pour Souris. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour ASPSCR1 anticorps (ABIN1724649)

Antigène: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ASPSCR1 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 4A11A6G11

Détail du produit anti-ASPSCR1 anticorps

Fonction: Mouse TUG Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of TUG expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-ASPSCR1 (ABIN1724649)

Bogan, Hendon, McKee, Tsao, Lodish: "Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking." dans: Nature, Vol. 425, Issue 6959, pp. 727-33, (2003) (PubMed).

Détails sur ASPSCR1

Antigène: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Autre désignation: TUG

Sujet: The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.

UniProt: Q9BZE9