BNP anticorps

N° du produit ABIN1724675

Détail du produit anti-BNP anticorps

Antigène: BNP (Brain Natriuretic Peptide (BNP))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BNP est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Séquence: Cys-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser

Immunogène: Synthetic peptide corresponding to aa (Cys-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser) of human BNP, conjugated to KLH.

Clone: 8D5B4C11

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, IHC: 1:200 - 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-BNP (ABIN1724675)

Dawson, Struthers: "Screening for treatable left ventricular abnormalities in diabetic patients." dans: Expert opinion on biological therapy, Vol. 3, Issue 1, pp. 107-12, (2003) (PubMed).

Pfister, Erdmann, Schneider: "[Natriuretic peptides BNP and NT-pro-BNP--the "new troponins" for estimation of heart failure?]." dans: Deutsche medizinische Wochenschrift (1946), Vol. 128, Issue 18, pp. 1007-12, (2003) (PubMed).

Détails sur BNP

Antigène: BNP (Brain Natriuretic Peptide (BNP))

Autre désignation: BNP (BNP Produits)

Synonymes: anticorps bnp, anticorps BNP1, anticorps NPPB, anticorps BNP, anticorps Bnf, anticorps AA408272, anticorps B-type natriuretic peptide, anticorps natriuretic peptide B, anticorps natriuretic peptide type B, anticorps nppb, anticorps NPPB, anticorps Nppb

Sujet:

Description: BNP (brain natriuretic peptide) belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. BNP circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. It is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic.

Aliases: BNP, NPPB

ID gène: 4879

HGNC: 4879

Pathways: Hormone Activity