CD20 anticorps

N° du produit ABIN1724682

Cet anticorps anti-CD20 est un anticorps Souris Monoclonal détectant CD20 dans IHC, ELISA et ICC. Adapté pour Humain. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour CD20 anticorps (ABIN1724682)

Antigène: CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD20 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Clone: 3E9D3C1G3

Détail du produit anti-CD20 anticorps

Fonction: CD20 Antibody

Séquence: EPANPSEKNS PSTQY

Purification: Ascitic fluid

Immunogène: Synthetic peptide corresponding to aa (EPANPSEKNSPSTQY) of human CD20,conjugated to KLH.

Isotype: IgG

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-CD20 (ABIN1724682)

Byar: "Educating patients about radioimmunotherapy with yttrium 90 ibritumomab tiuxetan (Zevalin)." dans: Seminars in oncology nursing, Vol. 20, Issue 1 Suppl 1, pp. 20-5, (2004) (PubMed).

Reiners, Hansen, Krüssmann, Schön, Csernok, Gross, Engert, Von Strandmann: "Selective killing of B-cell hybridomas targeting proteinase 3, Wegener's autoantigen." dans: Immunology, Vol. 112, Issue 2, pp. 228-36, (2004) (PubMed).

Détails sur CD20

Antigène: CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

Autre désignation: CD20

Sujet: CD20 (MS4A1, membrane-spanning 4-domains, subfamily A, member 1) is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 Molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit. And it is known to accelerate the G0 to G1 progression induced by IGF-1.

ID gène: 931

UniProt: P11836