EhpB1 (AA 19-133) anticorps

N° du produit ABIN1724690

Détail du produit

Antigène: EhpB1

Épitope: AA 19-133

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Purification: purified

Immunogène: Purified recombinant fragment of EphB1 (aa19-133) expressed in E. coli.

Clone: 5F10A4

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Référence

Huynh-Do, Vindis, Liu, Cerretti, McGrew, Enriquez, Chen, Daniel: "Ephrin-B1 transduces signals to activate integrin-mediated migration, attachment and angiogenesis." dans: Journal of cell science, Vol. 115, Issue Pt 15, pp. 3073-81, (2002) (PubMed).

Prevost, Woulfe, Tanaka, Brass: "Interactions between Eph kinases and ephrins provide a mechanism to support platelet aggregation once cell-to-cell contact has occurred." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 14, pp. 9219-24, (2002) (PubMed).

Détail du antigène

Antigène: EhpB1

Sujet:

Description: EhpB1: EPH receptor B1. It is a receptor for ephrin-B family members. Ephrin receptors and their ligands, the ephrins, medate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family.

Aliases: ELK, NET, Hek6, EPHT2, EPHB1

Poids moléculaire: 110 kDa

ID gène: 2047

HGNC: 2047