Estrogen Receptor alpha anticorps (AA 301-595)

N° du produit ABIN1724700

Cet anticorps anti-Estrogen Receptor alpha est un anticorps Souris Monoclonal détectant Estrogen Receptor alpha dans ELISA. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour Estrogen Receptor alpha anticorps (AA 301-595) (ABIN1724700)

Antigène: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Estrogen Receptor alpha est non-conjugé

Application: ELISA

Clone: 10H12B10

Détail du produit anti-Estrogen Receptor alpha anticorps

Épitope: AA 301-595

Fonction: ESR1 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of ESR1 (aa301-595) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Estrogen Receptor alpha (ABIN1724700)

Cepollaro, Lauretani, Gozzini, Masi, Falchetti, Del Monte, Carbonell-Sala, Tanini, Corsi, Bandinelli, Ferrucci, Brandi: "Relationship of volumetric bone mineral density and structural parameters with ERalpha gene polymorphisms." dans: Calcified tissue international, Vol. 80, Issue 5, pp. 307-15, (2007) (PubMed).

Détails sur Estrogen Receptor alpha

Antigène: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Autre désignation: ESR1

Sujet: ESR1: estrogen receptor 1. This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.

UniProt: P03372

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly