HSC70 Interacting Protein HIP anticorps

N° du produit ABIN1724716

Cet anticorps Souris Monoclonal détecte spécifiquement HSC70 Interacting Protein HIP dans WB, ELISA, IHC et ICC. Il présente une réactivité envers Humain et Singe et a été mentionné dans 1 publication.

Aperçu rapide pour HSC70 Interacting Protein HIP anticorps (ABIN1724716)

Antigène: HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))

Reactivité: Humain, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HSC70 Interacting Protein HIP est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: 3B10

Détail du produit anti-HSC70 Interacting Protein HIP anticorps

Fonction: ST13 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human ST13 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-HSC70 Interacting Protein HIP (ABIN1724716)

Zhou, Lucas, Chan, Issaq, Petricoin, Liotta, Veenstra, Conrads: "An investigation into the human serum "interactome"." dans: Electrophoresis, Vol. 25, Issue 9, pp. 1289-98, (2004) (PubMed).

Détails sur HSC70 Interacting Protein HIP

Antigène: HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))

Autre désignation: ST13

Sujet: ST13 (suppression of tumorigenicity protein 13), also known as Hip (HSP70-interacting protein), is one of several co-chaperones that regulate activities of the HSP70 chaperone family. The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family. By collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis.

Poids moléculaire: 48 kDa

ID gène: 6767

UniProt: P50502