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Cadherin 5 anticorps (AA 29-223)

CDH5 Reactivité: Humain, Souris WB, ELISA, FACS Hôte: Souris Monoclonal 3D5C7 unconjugated
N° du produit ABIN1724747
  • Antigène Voir toutes Cadherin 5 (CDH5) Anticorps
    Cadherin 5 (CDH5)
    Épitope
    • 16
    • 12
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 29-223
    Reactivité
    • 106
    • 68
    • 43
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 88
    • 33
    • 9
    • 1
    Souris
    Clonalité
    • 85
    • 46
    Monoclonal
    Conjugué
    • 73
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Cadherin 5 est non-conjugé
    Application
    • 89
    • 43
    • 39
    • 39
    • 26
    • 16
    • 16
    • 15
    • 14
    • 13
    • 12
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human CDH5 (AA: 29-223 ) expressed in E. coli.
    Clone
    3D5C7
    Isotype
    IgG1
    Top Product
    Discover our top product CDH5 Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Pirotte, Lamour, Lambert, Alvarez Gonzalez, Ormenese, Noël, Mottet, Castronovo, Bellahcène: "Dentin matrix protein 1 induces membrane expression of VE-cadherin on endothelial cells and inhibits VEGF-induced angiogenesis by blocking VEGFR-2 phosphorylation." dans: Blood, Vol. 117, Issue 8, pp. 2515-26, (2011) (PubMed).

    Shrivastava-Ranjan, Rollin, Spiropoulou: "Andes virus disrupts the endothelial cell barrier by induction of vascular endothelial growth factor and downregulation of VE-cadherin." dans: Journal of virology, Vol. 84, Issue 21, pp. 11227-34, (2010) (PubMed).

  • Antigène
    Cadherin 5 (CDH5)
    Autre désignation
    CDH5 (CDH5 Produits)
    Synonymes
    anticorps 7B4, anticorps AA408225, anticorps Cd144, anticorps VE-Cad, anticorps VECD, anticorps VEcad, anticorps Vec, anticorps wu:fc88a07, anticorps CD144, anticorps cadherin-5, anticorps cadherin 5, anticorps CDH5, anticorps Cdh5, anticorps cdh5
    Sujet

    Description: This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined. , ,

    Aliases: 7B4, CD144

    Poids moléculaire
    87.5 kDa
    ID gène
    1003
    HGNC
    1003
    Pathways
    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
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