NEUROD1 anticorps (AA 26-91)

N° du produit ABIN1724757

Cité dans 2 publications. Cet anticorps anti-NEUROD1 Monoclonal Souris (Clone 6E9G12) (ABIN1724757) détecte spécifiquement NEUROD1 dans ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Singe.

Aperçu rapide pour NEUROD1 anticorps (AA 26-91) (ABIN1724757)

Antigène: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Reactivité: Humain, Souris, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NEUROD1 est non-conjugé

Application: ELISA

Clone: 6E9G12

Détail du produit anti-NEUROD1 anticorps

Épitope: AA 26-91

Fonction: Neurod Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human Neurod (AA: 26-91 ) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-NEUROD1 (ABIN1724757)

Huang, Kishida, Cao, Murakami-Tonami, Mu, Nakaguro, Koide, Takeuchi, Onishi, Kadomatsu: "The neuronal differentiation factor NeuroD1 downregulates the neuronal repellent factor Slit2 expression and promotes cell motility and tumor formation of neuroblastoma." dans: Cancer research, Vol. 71, Issue 8, pp. 2938-48, (2011) (PubMed).

Shimoda, Chen, Noguchi, Matsumoto, Grayburn: "Neurogenic differentiation 1 directs differentiation of cytokeratin 19-positive human pancreatic nonendocrine cells into insulin-producing cells." dans: Transplantation proceedings, Vol. 42, Issue 6, pp. 2071-4, (2010) (PubMed).

Détails sur NEUROD1

Antigène: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Autre désignation: Neurod

Sujet: This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus.

Poids moléculaire: 40 kDa

UniProt: Q13562

Pathways: Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis