CBX8 anticorps (AA 17-222)
Aperçu rapide pour CBX8 anticorps (AA 17-222) (ABIN1724766)
Antigène
Voir toutes CBX8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 17-222
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Fonction
- CBX8 Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human CBX8 (AA: 17-222) expressed in E. Coli.
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Isotype
- IgG1
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus." dans: The EMBO journal, Vol. 26, Issue 6, pp. 1637-48, (2007) (PubMed).
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: "Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus." dans: The EMBO journal, Vol. 26, Issue 6, pp. 1637-48, (2007) (PubMed).
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- CBX8 (Chromobox Homolog 8 (CBX8))
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Autre désignation
- CBX8
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Sujet
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Chromobox homolog 8 (CBX8), a Polycomb Group protein that interacts with MLL-AF9 and TIP60, plays an essential role in MLL-AF9 transcriptional regulation and leukemogenesis. CBX8, which is part of one of the PRC1 complexes, regulates proliferation of diploid human and mouse fibroblasts through direct binding to the INK4A-ARF locus.
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Poids moléculaire
- 43.4 kDa
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ID gène
- 57332
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UniProt
- Q9HC52
Antigène
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