GUCY1A1 anticorps (AA 22-214)

N° du produit ABIN1724787

Cet anticorps anti-GUCY1A1 est un anticorps Souris Monoclonal détectant GUCY1A1 dans WB, ELISA, IHC, FACS et ICC. Adapté pour Humain. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour GUCY1A1 anticorps (AA 22-214) (ABIN1724787)

Antigène: GUCY1A1 (Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GUCY1A1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 3G6B2

Détail du produit anti-GUCY1A1 anticorps

Épitope: AA 22-214

Fonction: GUCY1A3 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human GUCY1A3 (AA: 22-214) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-GUCY1A1 (ABIN1724787)

Cai, Hsieh, Gao, Kannan, Bhansali, Govardhan, Dutta, Shemshedini: "Soluble guanylyl cyclase ?1 and p53 cytoplasmic sequestration and down-regulation in prostate cancer." dans: Molecular endocrinology (Baltimore, Md.), Vol. 26, Issue 2, pp. 292-307, (2012) (PubMed).

Zhong, Pan, Liu, Wang, Ying, Su, Huang, Tan: "A novel insight into the heme and NO/CO binding mechanism of the alpha subunit of human soluble guanylate cyclase." dans: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, Vol. 16, Issue 8, pp. 1227-39, (2011) (PubMed).

Détails sur GUCY1A1

Antigène: GUCY1A1 (Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1))

Autre désignation: GUCY1A3

Sujet: Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene.

Poids moléculaire: 77.5 kDa

ID gène: 2982

Pathways: Myometrial Relaxation and Contraction