Paired Box 3 anticorps (AA 142-203)

N° du produit ABIN1724816

1 publication est disponible pour ce produit. L’anticorps anti-Paired Box 3 Monoclonal produit chez le Souris a été validé pour WB et ELISA. Il convient pour la détection de Paired Box 3 dans des échantillons provenant de Humain et Souris. }

Aperçu rapide pour Paired Box 3 anticorps (AA 142-203) (ABIN1724816)

Antigène: Paired Box 3 (PAX3)

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Paired Box 3 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 7D8G7

Détail du produit anti-Paired Box 3 anticorps

Épitope: AA 142-203

Fonction: PAX3 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human PAX3 (AA: 142-203) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Paired Box 3 (ABIN1724816)

Dong, Li, Cao, Liu, Pier, Chen, Xu, Chen, Wang, Cui: "FGF2 regulates melanocytes viability through the STAT3-transactivated PAX3 transcription." dans: Cell death and differentiation, Vol. 19, Issue 4, pp. 616-22, (2012) (PubMed).

Détails sur Paired Box 3

Antigène: Paired Box 3 (PAX3)

Autre désignation: PAX3

Sujet: This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.

Poids moléculaire: 53 kDa

UniProt: P23760

Pathways: Sensory Perception of Sound, Tube Formation